Exploring Hope: Parkinson’s & Movement Disorders Research Hub
Welcome to our hub of hope and discovery in Parkinson’s Disease and movement disorders research. Here, we’re unlocking secrets and paving pathways for new treatments, hand-in-hand with collaborators from high schools, College Projects, University PhD Works to prestigious institutions. Whether you’re a patient, a student eager to explore research, or an institution seeking collaboration, you’re welcomed with open arms. Dive into our ongoing projects, where every milestone is a step forward in our shared journey. We invite patients, families, and students alike to join us in shaping the future of research. Together, let’s make a difference—one step at a time.
Anyone who is considering taking part in research should speak to the professionals managing the project for more in-depth information.
The information we provided is only for your consideration. It should not be treated as advice or a recommendation to participate in any of the studies.
Ready to join?
We welcome you to reach out and join our community. Contact us today to learn more about how you can get involved. Together, let’s pave the way towards a brighter tomorrow.
Joining the network requires no commitment. Google form: https://forms.gle/9JE4pFHGvjtPiaUY9
If you have any questions, get in touch with the research team at drprashanth.lk@movementdisordersclinic.com
High School Projects
Simple projects or Research Orientation for high school students as part of vacation programs or year long goal oriented works to build profiles for their future careers
College & University Projects
College projects or works as part of individual research interests, to learn about a subspecialty, work on thesis/dissertations, PhD work collaborations etc
Institutional Collaborations
Projects and works as part of institutional research teams / Scientists requirements.
Current Ongoing Projects
Geneome Wide Association Study
Genome Wide Association Study of Parkinson's Disease
Understanding the Palliative Care Requirements
Palliative Care Requirements
Genetics of Young Onset Parkinson's Disease
Genetics of Young Onset Parkinson's Disease (GOPI-YOPD)
Exercise Patterns in Parkinson's Disease
Understanding Exercise Pattern in Parkinson's Disease
Huntington Disease Registry
Huntington disease registry
School Projects
High School Projects
Looking to delve into the fascinating world of neuroscience? Our school projects offer an exclusive opportunity for high school students to immerse themselves in cutting-edge research focused on Parkinson’s disease and neurodegeneration.
Over the course of 2-6 weeks, students will have the unique chance to work closely with experts at our clinic. From observing ongoing research to collecting data and understanding project methodologies, participants will gain invaluable insights into the field of neuroscience.
The experience doesn’t stop there. Students will also have the opportunity to showcase their findings by preparing abstracts or posters for scientific conferences—a remarkable chance to share their discoveries with the wider scientific community.
Ideal for vacation time, our program allows for flexibility, with the option to extend projects into weekends during the school term.
Works Done by Students
Veena Karthik, D. Hosakere Sreenivasa, P. Kukkle. Are Indians Geared Up for the Healthcare Expenses of Ageing Disorders? AOPMC 2023, Abstracts – 80. Mov Disord Clin Pract, 10: S9-S122. https://doi.org/10.1002/mdc3.13679
College / University Projects (Undergraduates and Post Graduates)
College & University Projects
Embark on an immersive journey into neuroscience research with our college and university projects, tailored for science students, medical residents, and engineering enthusiasts keen on neurosciences.
Our projects offer an in-depth exploration aimed at guiding participants through the entire research process, from inception to completion of a research paper. Ideal for those seeking to deepen their understanding and make meaningful contributions to the field.
Key highlights include:
- Comprehensive Research: Dive into projects focusing on Parkinson’s disease and neurodegeneration, designed to equip you with the skills and knowledge necessary for conducting research papers.
- Professional Collaboration: Benefit from collaboration opportunities for dissertations and PhD theses in conjunction with parent institutes, providing access to extensive resources and mentorship.
- Extended Commitment: Engage in longer-term commitments, involving both clinic observations and dedicated work during leisure time, ensuring thorough project completion and skill development.
- Tailored for Growth: Tailored for ambitious individuals seeking to push boundaries and contribute meaningfully to the scientific community.
Elevate your academic journey and explore the frontiers of neuroscience research with us. Join our projects today and unlock endless possibilities for academic and professional growth.
Works Done by Students
BS Sneha, S Karthikbabu, N Syed, LK Prashanth. Effects of trunk proprioceptive neuromuscular facilitation on dynamic balance, mobility and quality of life in Parkinson’s disease Parkinsonism & Related Disorders 2016;22:e68-e69
B Shetty, S. Mittal, P. Kukkle. Knowledge, Attitude and Practices about Movement Disorders in India. Movement Disorders. 2019;34(S2):757-58.
Raju S, Ravi A, Prashanth LK. Cervical Dystonia mimics: A case series and review of literature. Tremor Other Hyperkinet Mov. 2019;9. Doi: 10.7916/tohm.v0.707
Faisal M and Kukkle PL, Hypoparathyroidism Masquerading as Corticobasal Syndrome. Mov Disord Clin Pract; 2021: https://doi.org/10.1002/mdc3.13182
Telugu T, Sreenivasa D, Sriram D, Raju S, Ramakrishna A, Kukkle P. Are patients with Parkinson’s disease in India exercising enough? AOPMC 2023, Abstracts – 44. Mov Disord Clin Pract, 10: S9-S122. https://doi.org/10.1002/mdc3.13679
Institutional Collaborative Works
Collaboration with Raja Rajeswari Medical College
Prabhakara S, Hanumantha Rao HM, Prashanth LK, Anbazhagan K, Jacques R, Reddy BK. PRRT2 Gene Mutations in Indian Paroxysmal Kinesigenic Dyskinesia Patients. Ann Indian Acad Neurol. 2021 May-Jun;24(3):425-429. doi: 10.4103/aian.AIAN_417_20
Engineering Projects
Akshay S, Amudha J, Kulkarni N, Prashanth LK. (2023). iSTIMULI: Prescriptive Stimulus Design for Eye Movement Analysis of Patients with Parkinson’s Disease. In: Morusupalli, R., Dandibhotla, T.S., Atluri, V.V., Windridge, D., Lingras, P., Komati, V.R. (eds) Multi-disciplinary Trends in Artificial Intelligence. MIWAI 2023. Lecture Notes in Computer Science(), vol 14078. Springer, Cham. https://doi.org/10.1007/978-3-031-36402-0_55
Parkinson Research Alliance of India (PRAI)
- Kukkle PL, Goyal V, Geetha TS, Mridula KR, Kumar H, Borgohain R, Mukherjee A, Wadia PM, Yadav R, Desai S, Kumar N, Gupta R, Biswas A, Pal PK, Muthane U, Das SK, Quinn N, Ramprasad VL; Parkinson Research Alliance of India (PRAI). Clinical Study of 668 Indian Subjects with Juvenile, Young, and Early Onset Parkinson’s Disease. Can J Neurol Sci. 2022 Jan;49(1):93-101. doi: 10.1017/cjn.2021.40. Epub 2021 Mar 9. PMID: 33685545.
- Kukkle PL, Geetha TS, Chaudhary R, Sathirapongsasuti JF, Goyal V, Kandadai RM, Kumar H, Borgohain R, Mukherjee A, Oliver M, Sunil M, Mootor MFE, Kapil S, Mandloi N, Wadia PM, Yadav R, Desai S, Kumar N, Biswas A, Pal PK, Muthane UB, Das SK, Sakthivel Murugan SM, Peterson AS, Stawiski EW, Seshagiri S, Gupta R, Ramprasad VL, Prai PRAOI. Genome-Wide Polygenic Score Predicts Large Number of High Risk Individuals in Monogenic Undiagnosed Young Onset Parkinson’s Disease Patients from India. Adv Biol (Weinh). 2022 Jul 10:e2101326. doi: 10.1002/adbi.202101326.
- Andrews SV, Kukkle PL, Menon R, Geetha TS, Goyal V, Kandadai RM, Kumar H, Borgohain R, Mukherjee A, Wadia PM, Yadav R, Desai S, Kumar N, Joshi D, Murugan S, Biswas A, Pal PK, Oliver M, Nair S, Kayalvizhi A, Samson PL, Deshmukh M, Bassi A, Sandeep C, Mandloi N, Davis OB, Roberts MA, Leto DE, Henry AG, Di Paolo G, Muthane U, Das SK, Peterson AS, Sandmann T, Gupta R, Ramprasad VL; Parkinson Research Alliance of India (PRAI). The Genetic Drivers of Juvenile, Young, and Early-Onset Parkinson’s Disease in India. Mov Disord. 2023 Nov 28. doi: 10.1002/mds.29676. Epub ahead of print. PMID: 38014556.
Collaboration with Medgenome Labs
- Prashanth LK, Murugan S, Kamath V, Gupta R, Jadav R, Sreekantaswamy S, Ramprasad VL. First report of Kufor-Rakeb Syndrome (PARK 9) from India, and a Novel Nonsense Mutation in ATP13A2 gene. Mov Disord Clin Pract. 2015 May 9;2(3):326-327
- Prashanth LK, Thenral SG, Mahadevan A, Ramprasad VL. A case of Autosomal Dominant Ataxia with Vocal cord palsy due to mutation in PRNP gene. Mov Disord Clin Pract. 2020 Mov Disord Clin Pract. 2020 Jul 27;7(6):688-692. doi: 10.1002/mdc3.12999
- Abbas MM, Thenral SG, Ramprasad VL, Walker RH, Kukkle PL. Chorea-acanthocytosis: 3 New Families with Novel Genetic and Metabolic Findings. Ann Indian Acad Neurol. 2021 May-Jun;24(3):452-456. doi: 10.4103/aian.AIAN_215_20. Epub 2021 Mar 27. PMID: 34447025; PMCID: PMC8370142.
- Olszewska DA, Shetty R, Geetha TS, Ramprasad VL, Lang AE, Kukkle PL. Oculogyric Crisis Phenotype of Levodopa-Induced Ocular Dyskinesia. Mov Disord Clin Pract. 2022 Feb 10;9(3):390-393. doi: 10.1002/mdc3.13416. PMID: 36989007; PMCID: PMC8974885.
Collaboration with Other Movement Disorders Centers
- Kukkle PL, Park HK, Obaid MT, Fujioka S. The chronicles of modern movement disorders in India. Ann Mov Disord 2019;2:1-8.
- Kumar, P. Wadia, H. Kumar, P. Kukke, S. Gupta, V. Goyal, A. Raza, A. Zuzek, A. Patel. Practice Patterns with Onabotulinum Toxin-A for Movement disorders: South Asian Neurologist Survey. Movement Disorders. 2019;34(S2):55.
- Prashanth LK, Hrishikesh Kumar, Pettarusp M Wadia, Muthane U. The Spectrum of movement disorders in tertiary care centers in India : A tale of three cities. Ann Indian Acad Neurol. 2021 Sep-Oct;24(5):721-725. doi: 10.4103/aian.AIAN_1257_20.
- Wadia PM, Mathur V, Kukkle PL, Khanna JN. Task-specific oromandibular dystonia secondary to chewing Khat (Catha edulis)- A series of 35 cases. Parkinsonism Relat Disord. 2023 Sep;114:105806. doi: 10.1016/j.parkreldis.2023.105806. Epub 2023 Aug 16. PMID: 37619301.